Diabetes, Exercise and Liver Fat (DELIVER)
Principal Investigator: Dr James King
Study start date: September 2018
We know that becoming overweight can lead to liver problems and this risk is increased if an individual also has type 2 diabetes. The DELIVER study will compare liver related health in overweight or obese men who either do, or do not, have type 2 diabetes. The DELIVER study will also determine whether exercise training can improve liver health in individuals with type 2 diabetes.
What does the study involve?
Participation will involve study visits to the University of Nottingham and the Queens Medical Centre (Nottingham) or Leicester General Hospital (whichever is closer). Overweight or obese individuals without type 2 diabetes will have 2 study visits. Individuals with type 2 diabetes will additionally repeat these visits after a six-week intervention of exercise or control (usual lifestyle).
Measurements within this study include: MRI scan (abdominal region), body weight/composition, fasting blood sample, aerobic fitness test, lifestyle related questionnaires, medical evaluation, habitual physical activity and dietary intake. Participants will be provided with detailed feedback regarding their health and lifestyle and all travel expenses will be covered during the study.
Who can take part?
This study is recruiting non-smoking males (aged 30 – 75 years) who do not regularly perform exercise who fall into the following groups:
- Overweight or obese
- With pre-diabetes or type 2 diabetes
If you fall into either of these groups and would like to know more about the study please contact the study team on 01509 228457 or email J.A.King@lboro.ac.uk
This study is funded by Diabetes UK and supported by the NIHR Leicester Biomedical Research Centre.